Research Project

지원기관
한국연구재단 (교육과학기술부)
사업명/역할
일반연구 / 연구책임
수행년도
2010-05-01 ~ 2013-04-30
과제명
폴리유비퀴틴 유전자 Ubc의 결손이 조혈모세포 및 양기능성(bipotent) 태아 간 상피기원세포의 기능 및 증식에 미치는 영향

대표 성과물

논문
3. Disruption of polyubiquitin gene Ubc leads to defective proliferation of hepatocytes and bipotent fetal liver epithelial progenitor cells
Hyejin Park, Min-Sik Yoon, Kwon-Yul Ryu
Biochemical and Biophysical Research Communications , 2013 , 435(3) , 434–440 , Link
2. Locus coeruleus neurons are resistant to dysfunction and degeneration by maintaining free ubiquitin levels although total ubiquitin levels decrease upon disruption of polyubiquitin gene Ubb
Chul-Woo Park, Han-Wook Ryu, Kwon-Yul Ryu
Biochemical and Biophysical Research Communications , 2012 , 418(3) , 541–546 , Link
1. Perturbation of the hematopoietic system during embryonic liver development due to disruption of polyubiquitin gene Ubc in mice
Kwon-Yul Ryu, Hyejin Park, Derrick J Rossi, Irving L Weissman, Ron R Kopito
PLOS One , 2012 , 7(2) , e32956 , Link