64. A novel strategy to overcome neurodegenerative diseases by reduced secretion of lipocalin-2 from reactive astrocytes 국내
Kwon-Yul Ryu
2024 KSBMB Autophagy Symposium, 2024.08.20~2024.08.22, 강릉, 대한민국, 2024
63. Elucidation of the role of signal peptide originated from secretory protein lipocalin-2 국내
Taek-Yeong Kim, Kwon-Yul Ryu
The 21st Conference on Protein Metabolism & Diseases, 2024.07.01~2024.07.03, 양양, 대한민국, 2024
62. Neurodegenerative and neuroinflammatory phenotypes of polyubiquitin gene Ubb knockout mice 국내
Jin-Sil Bae, Kwon-Yul Ryu
The 21st Conference on Protein Metabolism & Diseases, 2024.07.01~2024.07.03, 양양, 대한민국, 2024
61. Study of gene expression regulation in nerve cells using ENCODE analysis 국내
Ye-Jin Cho, Kwon-Yul Ryu
The 21st Conference on Protein Metabolism & Diseases, 2024.07.01~2024.07.03, 양양, 대한민국, 2024
우수발표상
60. Investigation of the internalization of lipocalin-2 through its receptor in primary neurons 국내
Jin-Sil Bae, Ye-Jin Cho, Taek-Yeong Kim, Kwon-Yul Ryu
2023 International Conference of the Korean Society for Molecular and Cellular Biology, 2023.11.06~2023.11.08, 제주, 대한민국, 2023
59. Determination of the function of signal peptide: extracellular secretion and degradation by autophagy 국내
Taek-Yeong Kim, Kwon-Yul Ryu
The 20th Conference on Protein Metabolism & Diseases, 2023.07.03~2023.07.05, 양양, 대한민국, 2023
58. Effects of glycosylation on synthesis, degradation, and function of lipocalin-2 국내
Ye-Jin Cho, Kwon-Yul Ryu
The 20th Conference on Protein Metabolism & Diseases, 2023.07.03~2023.07.05, 양양, 대한민국, 2023
57. Isolation and culture of mixed and pure astrocytes from the mouse brain 국내
Ye-Jin Cho, Kwon-Yul Ryu
The 20th Conference on Protein Metabolism & Diseases, 2023.07.03~2023.07.05, 양양, 대한민국, 2023
우수발표상
56. Altered astrocyte reactivity by proteasome inhibition alleviates inflammation-induced neuronal damages through reduction of neurotoxic lipocalin-2 국내
Byung-Kwon Jung, Jin-Sil Bae, Kwon-Yul Ryu
The 19th Protein Metabolism & Diseases Conference, 2022.08.25~2022.08.26, 경주, 대한민국, 2022
55. Effects of altered protein polyubiquitination on production, degradation and secretion of lipocalin-2 국내
Ye-Jin Cho, Byung-Kwon Jung, Kwon-Yul Ryu
The 19th Protein Metabolism & Diseases Conference, 2022.08.25~2022.08.26, 경주, 대한민국, 2022
54. Hampering retrograde transport of polystyrene nanoplastics along microtubules promotes their removal via exocytosis and reduces cytotoxicity 국내
Seung-Woo Han, Kwon-Yul Ryu
The 19th Protein Metabolism & Diseases Conference, 2022.08.25~2022.08.26, 경주, 대한민국, 2022
53. The suppressive effect of bortezomib on LPS-induced lipocalin-2 in vivo 국내
Jin-Sil Bae, Ji-Eun Heo, Kwon-Yul Ryu
The 19th Protein Metabolism & Diseases Conference, 2022.08.25~2022.08.26, 경주, 대한민국, 2022
52. Increased clearance of non-biodegradable polystyrene nanoplastics by exocytosis through the inhibition of their retrograde transport inside cells 국내
Seung-Woo Han, Byung-Kwon Jung, Jin-Sil Bae, Ye-Jin Cho, Kwon-Yul Ryu
The 12th Korean Society for Biochemistry and Molecular Biology Winter Workshop, 20220112~2022014, 홍천, 대한민국, 2022
51. Improvement of neuronal viability with increased levels of free ubiquitin under proteotoxic stress induced by amyloid beta aggregates 국내
Chul-Woo Park, Byung-Kwon Jung, Kwon-Yul Ryu
The 31st Korean Society for Molecular and Cellular Biology Winter Conference 2020, 20200115~20200117, 용평, 대한민국, 2020
50. In vitro monitoring of cellular effects directly induced by microplastic exposure 국내
Byung-Kwon Jung, Seung-Woo Han, So-Hyun Park, Jin-Sil Bae, Jinhee Choi, Kwon-Yul Ryu
The 31st Korean Society for Molecular and Cellular Biology Winter Conference 2020, 20200115~20200117, 용평, 대한민국, 2020
49. Disruption of the polyubiquitin gene Ubb leads to failure of sperm development due to ubiquitin-homeostasis collapse 국내
Byung-Kwon Jung, Kwon-Yul Ryu
17th Protein Metabolism & Diseases Conference, 20190829~20190831, 삼척, 대한민국, 2019
48. Optimization of the endogenous UBC upregulation using a modified CRISPR/Cas9 system 국내
So-Hyun Park, Kwon-Yul Ryu
17th Protein Metabolism & Diseases Conference, 20190829~20190831, 삼척, 대한민국, 2019
47. Simultaneous disruption of two polyubiquitin genes significantly impairs the proteasome function and cellular proliferation 국내
Jin-Sil Bae, Kwon-Yul Ryu
17th Protein Metabolism & Diseases Conference, 20190829~20190831, 삼척, 대한민국, 2019
46. Ubiquitin deficiency leads to reduced capacity in the self-renewal of neural stem cells 국내
Chul-Woo Park, Kwon-Yul Ryu
17th Protein Metabolism & Diseases Conference, 20190829~20190831, 삼척, 대한민국, 2019
45. Upregulation of the polyubiquitin gene UBC under normal conditions via modified inducible CRISPR/Cas9 system 국내
Seung-Woo Han, Kwon-Yul Ryu
17th Protein Metabolism & Diseases Conference, 20190829~20190831, 삼척, 대한민국, 2019
44. Polyubiquitin gene Ubb knockdown leads to abnormal neural differentiation, but not developmental defects of neuronal cells in vitro 국내
Byung-Kwon Jung, Kwon-Yul Ryu
2018 Summer Workshop of the Korean Chemical Society – Life Chemistry Division, 20180621~20180623, 강릉, 대한민국, 2018
우수발표상
43. Reduced proteasome activity via ubiquitin depletion using CRISPR-Cas9 gene editing 국내
Chul-Woo Park, Kwon-Yul Ryu
2018 Summer Workshop of the Korean Chemical Society – Life Chemistry Division, 20180621~20180623, 강릉, 대한민국, 2018
42. Transcriptional regulation of endogenous polyubiquitin genes using a modified CRISPR-Cas9 system 국내
Seung-Woo Han, Byung-Kwon Jung, Kwon-Yul Ryu
The 121th General Meeting of the Korean Chemical Society, 20180418~20180420, 제주, 대한민국, 2018
41. Cellular ubiquitin is a key protein to determine the fate of neural stem cells, but exerts no effect on the maturation of already differentiated neurons 국내
Kwon-Yul Ryu
2018 Winter Workshop of the Korean Chemical Society – Life Chemistry Division, 20180129~20180130, 서울, 대한민국, 2018
40. Neural stem cell differentiation is affected by the reduced levels of cellular ubiquitin 국내
Chul-Woo Park, Kwon-Yul Ryu
2017 International Protein Metabolism & Diseases Conference, 20170706~20170708, 양양, 대한민국, 2017
39. Reduced ubiquitin pool results in dysregulation of neural stem cell differentiation, but not neuronal development 국내
Byung-Kwon Jung, Kwon-Yul Ryu
2017 International Protein Metabolism & Diseases Conference, 20170706~20170708, 양양, 대한민국, 2017
38. Effect of altered cellular ubiquitin quantity on neural stem cell differentiation 국외
Chul-Woo Park, Kwon-Yul Ryu
Cold Spring Harbor Meeting on the Ubiquitin Family, 20170418~20170422, Cold Springs Harbor, New York, USA, 2017
37. p62 polyubiquitination is required for autophagic flux and cellular survival under oxidative stress induced by arsenite 국외
Hyuna Lee, Kwon-Yul Ryu
Cold Spring Harbor Meeting on the Ubiquitin Family, 20170418~20170422, Cold Springs Harbor, New York, USA, 2017
36. Temporal downregulation of polyubiquitin gene Ubb affects neuronal differentiation, but not their maturation, in cells cultured in vitro 국외
Byung-Kwon Jung, Kwon-Yul Ryu
Cold Spring Harbor Meeting on the Ubiquitin Family, 20170418~20170422, Cold Springs Harbor, New York, USA, 2017
35. Effect of cellular ubiquitin level on the regulation of oxidative stress response via Nrf1 국내
Donghee Lee, Kwon-Yul Ryu
2016 International Conference of the Korean Society for Molecular and Cellular Biology, 20161012~20161014, 서울, 대한민국, 2016
우수포스터상
34. Effect of Ubb knockdown on neuronal differentiation and development due to altered Notch signaling pathway 국내
Byung-Kwon Jung, Kwon-Yul Ryu
2016 International Conference of the Korean Society for Molecular and Cellular Biology, 20161012~20161014, 서울, 대한민국, 2016
우수포스터상
33. Competitive actions between Nrf1 and Nrf2 control the cytoprotective response against oxidative stress 국내
Donghee Lee, Kwon-Yul Ryu
The 13th Protein Metabolism & Diseases Conference, 20150708~20150709, 속초, 대한민국, 2015
32. Effect of p62/SQSTM1 polyubiquitination on its oligomer formation under oxidative stress 국내
Hyuna Lee, Kwon-Yul Ryu
The 13th Protein Metabolism & Diseases Conference, 20150708~20150709, 속초, 대한민국, 2015
31. Effect of Ubb knockdown on neural stem cell differentiation and neuronal development 국내
Byung-Kwon Jung, Kwon-Yul Ryu
The 13th Protein Metabolism & Diseases Conference, 20150708~20150709, 속초, 대한민국, 2015
30. Reduced levels of ubiquitin affect neural stem cell differentiation 국내
Chul-Woo Park, Han-Wook Ryu, Byung-Kwon Jung, Kwon-Yul Ryu
The 13th Protein Metabolism & Diseases Conference, 20150708~20150709, 속초, 대한민국, 2015
29. A potential role of ubiquitin as a sensor to regulate the proteasome activity 국내
Jin-Sil Bae, Kwon-Yul Ryu
KSBMB International Conference 2015, 20150512~20150514, 서울, 대한민국, 2015
28. Identification and characterization of the proteasome target protein for the regulation of neural stem cell differentiation 국내
Minji Kim, Kwon-Yul Ryu
KSBMB International Conference 2015, 20150512~20150514, 서울, 대한민국, 2015
27. Activation of the Nrf2-Keap1 pathway is not sufficient to confer resistance against cytotoxicity induced by arsenite when cellular ubiquitin levels are reduced 국내
Juhee Choi, Mi-Nam Kim, Han-Wook Ryu, Kwon-Yul Ryu
. The 6th Korean Society for Biochemistry and Molecular Biology Winter Workshop, 20150114~20150116, 하이원리조트, 대한민국, 2015
26. Cellular levels of free ubiquitin affect the vulnerability to inflammatory stress 국내
Chul-Woo Park, Han-Wook Ryu, Kwon-Yul Ryu
. The 6th Korean Society for Biochemistry and Molecular Biology Winter Workshop, 20150114~20150116, 하이원리조트, 대한민국, 2015
25. Effect of cellular ubiquitin levels on the differentiation of neural stem cells and neuronal development 국내
Han-Wook Ryu, Chul-Woo Park, Kwon-Yul Ryu
. The 6th Korean Society for Biochemistry and Molecular Biology Winter Workshop, 20150114~20150116, 하이원리조트, 대한민국, 2015
우수포스터상
24. Dysregulation of neural stem/progenitor cell differentiation with premature gliogenesis and impaired neuronal development due to disruption of polyubiquitin gene Ubb 국내
Han-Wook Ryu, Chul-Woo Park, Kwon-Yul Ryu
2014 International Conference on Protein Metabolism & Diseases, 20140709~20140711, 양양, 대한민국, 2014
23. Effect of cellular ubiquitin levels on the proteasomal function to confer resistance against cytotoxicity induced by arsenite 국내
Juhee Choi, Mi-Nam Kim, Han-Wook Ryu, Kwon-Yul Ryu
2014 International Conference on Protein Metabolism & Diseases, 20140709~20140711, 양양, 대한민국, 2014
22. Role of polyubiquitin gene Ubb to overcome inflammatory stress in mice 국내
Chul-Woo Park, Han-Wook Ryu, Kwon-Yul Ryu
2014 International Conference on Protein Metabolism & Diseases, 20140709~20140711, 양양, 대한민국, 2014
21. Loss of polyubiquitin gene Ubb causes dysregulation in neural stem cell fate determination: implications for premature brain ageing? 국내
Kwon-Yul Ryu
2013 Autumn Conference of the Korean Society for Gerontology, 20131107~20131108, 서울, 대한민국, 2013
초청발표
20. Cytoprotective effect of polyubiquitin genes via Nrf2-dependent and independent pathways under oxidative stress 국내
Mi-Nam Kim, Juhee Choi, Kwon-Yul Ryu
International conference of the Korean Society for Molecular and Cellular Biology, 20131009~20131011, 서울, 대한민국, 2013
19. Disruption of polyubiquitin gene Ubb leads to brain inflammation in mice 국내
Chul-Woo Park, Han-Wook Ryu, Kwon-Yul Ryu
International conference of the Korean Society for Molecular and Cellular Biology, 20131009~20131011, 서울, 대한민국, 2013
18. Impairment in neuronal development with disruption of polyubiquitin gene Ubb 국내
Han-Wook Ryu, Kwon-Yul Ryu
The 11th Protein Kinesis and Disease Symposium, 20130704~20130705, 대천, 대한민국, 2013
17. Effect of cellular ubiquitin levels on the oxidative stress response system regulated by the Nrf2-Keap1 pathway 국외
Mi-Nam Kim, Han-Wook Ryu, Kwon-Yul Ryu
The 2012 Annual Meeting of the American Society for Cell Biology, 20121215~20121219, San Francisco, California, USA, 2012
16. Impairment in neuronal development with disruption of polyubiquitin gene Ubb 국외
Han-Wook Ryu, Kwon-Yul Ryu
The 2012 Annual Meeting of the American Society for Cell Biology, 20121215~20121219, San Francisco, California, USA, 2012
15. Disruption of polyubiquitin gene Ubc does not lead to the failure in the fetal liver hematopoietic system, but leads to the defective proliferation in bipotent fetal liver epithelial progenitor cells 국내
Kwon-Yul Ryu
The 8th Symposium of Life Science at University of Seoul, 20121116~20121116, 서울, 대한민국, 2012
14. Ubiquitin deficiency and neurodegenerative diseases 국외
Kwon-Yul Ryu
TMU-UOS Bio-Meeting 2013, 20121128~20121128, Tokyo, Japan, 2012
초청발표
13. Effect of polyubiquitin gene Ubc disruption on fetal liver development in mice 국내
Hyejin Park, Kwon-Yul Ryu
The 10th Protein Kinesis and Disease Symposium, 20120705~20120706, 대천, 대한민국, 2012
12. Ubiquitin as a therapeutic target for neurological disorders 국내
Kwon-Yul Ryu
The 3rd Korean Society for Biochemistry and Molecular Biology Winter Workshop, 20120111~20120113, 하이원리조트, 대한민국, 2012
11. Disruption of polyubiquitin gene Ubb leads to abnormal hyperactivation of pro-inflammatory cytokine signaling in cultured neurons/astrocytes 국내
Han-Wook Ryu, Kwon-Yul Ryu
The 23rd Annual Meeting of the Korean Society for Molecular and Cellular Biology, 20111006~20111007, 서울, 대한민국, 2011
10. Polyubiquitin gene Ubc is essential for the proliferation and differentiation of fetal liver epithelial progenitor cells 국내
Hyejin Park, Kwon-Yul Ryu
The 23rd Annual Meeting of the Korean Society for Molecular and Cellular Biology, 20111006~20111007, 서울, 대한민국, 2011
9. Ubiquitin deficiency, brain inflammation and metabolic disorders 국내
Kwon-Yul Ryu
The 9th Protein Kinesis and Disease Symposium, 2011707~20110708, 대천, 대한민국, 2011
8. Effect of polyubiquitin gene Ubc disruption on function and proliferation of hematopoietic stem cells and fetal liver epithelial progenitor cells 국외
Kwon-Yul Ryu, Derrick J Rossi, Sun Young Kim, Ron R Kopito
The 6th Cold Spring Harbor Meeting on the Ubiquitin Family, 20110517~20110521, Cold Springs Harbor, New York, USA, 2011
7. Monitoring the stress response of polyubiquitin genes with a simple fluorescence plate reader-based assay 국내
Han-Wook Ryu, Kwon-Yul Ryu
The 22nd Annual Meeting of the Korean Society for Molecular and Cellular Biology, 20101007~20101008, 서울, 대한민국, 2010
6. Role of ubiquitin in neuroprotection 국내
Kwon-Yul Ryu
The 105th National Meeting of the Korean Chemical Society, 20100429~20100430, 인천, 대한민국, 2010
5. Development of a fluorescence-based assay to monitor stress response in mice 국내
Han-Wook Ryu, Kwon-Yul Ryu
The 21st Annual Meeting of the Korean Society for Molecular and Cellular Biology, 20091015~20091016, 서울, 대한민국, 2009
4. Loss of polyubiquitin gene Ubb leads to global alterations in hypothalamic function 국내
Kwon-Yul Ryu
The 21st Annual Meeting of the Korean Society for Molecular and Cellular Biology, 20091015~20091016, 서울, 대한민국, 2009
3. Can ubiquitin be a therapeutic target for neurological disorders? 국내
Kwon-Yul Ryu
The 4th International Symposium of Life Science at University of Seoul, 20081011~20071011, 서울, 대한민국, 2008
2. Disruption of polyubiquitin gene Ubb leads to adult-onset obesity with hypothalamic neurodegeneration and infertility in mice 국외
Kwon-Yul Ryu
2007 KOLIS Annual Meeting, 20070811~20070811, Berkeley, California, USA, 2007
1. Polyubiquitin B gene is required for energy homeostasis in mice 국외
Kwon-Yul Ryu, Gregory S Barsh, Ron R Kopito
FASEB Summer Research Conferences, 20060722~20060727, Saxtons River, Vermont, USA, 2006