Research Project

지원기관
한국보건산업진흥원 (보건복지부)
사업명/역할
질환극복기술개발사업 / 연구책임
수행년도
2014-12-01 ~ 2017-10-31
과제명
유비퀴틴에 의한 신경세포 및 아교세포 생성 제어를 통한 퇴행성 뇌질환 극복 기술 개발

대표 성과물

논문
6. A gold nanoparticle-mediated rapid in vitro assay of anti-aggregation reagents for amyloid β and its validation
Hye Young Kim, Donghee Lee, Kwon-Yul Ryu, Inhee Choi
Chemical Communications , 2017 , 53(32) , 4449–4452 , Link
5. Cytoprotective role of ubiquitin against toxicity induced by polyglutamine-expanded aggregates
Jin-Sil Bae, Kwon-Yul Ryu
Biochemical and Biophysical Research Communications , 2018 , 500(2) , 344–350 , Link
4. Effect of cellular ubiquitin levels on the regulation of oxidative stress response and proteasome function via Nrf1
Donghee Lee, Kwon-Yul Ryu
Biochemical and Biophysical Research Communications , 2017 , 485(2) , 234–240 , Link
3. Regulation of REST levels overcomes dysregulation of neural stem cell differentiation caused by disruption of polyubiquitin gene Ubb
Minji Kim, Kwon-Yul Ryu
Biochemical and Biophysical Research Communications , 2017 , 486(1) , 171–177 , Link
2. Temporal downregulation of the polyubiquitin gene Ubb affects neuronal differentiation, but not maturation, in cells cultured in vitro
Byung-Kwon Jung, Chul-Woo Park, Kwon-Yul Ryu
Scientific Reports , 2018 , 8 , 2629 , Link
1. Ubiquitin homeostasis: from neural stem cell differentiation to neuronal development
Han-Wook Ryu, Kwon-Yul Ryu
Neural Regeneration Research , 2015 , 10(8) , 1209–1210 , Link