지원기관
한국보건산업진흥원 (보건복지부)
사업명/역할
질환극복기술개발사업 / 연구책임
수행년도
2014-12-01 ~ 2017-10-31
과제명
유비퀴틴에 의한 신경세포 및 아교세포 생성 제어를 통한 퇴행성 뇌질환 극복 기술 개발
대표 성과물
논문
6. A gold nanoparticle-mediated rapid in vitro assay of anti-aggregation reagents for amyloid β and its validation
Hye Young Kim, Donghee Lee, Kwon-Yul Ryu, Inhee Choi
5. Cytoprotective role of ubiquitin against toxicity induced by polyglutamine-expanded aggregates
Jin-Sil Bae, Kwon-Yul Ryu
4. Effect of cellular ubiquitin levels on the regulation of oxidative stress response and proteasome function via Nrf1
Donghee Lee, Kwon-Yul Ryu
3. Regulation of REST levels overcomes dysregulation of neural stem cell differentiation caused by disruption of polyubiquitin gene Ubb
Minji Kim, Kwon-Yul Ryu
2. Temporal downregulation of the polyubiquitin gene Ubb affects neuronal differentiation, but not maturation, in cells cultured in vitro
Byung-Kwon Jung, Chul-Woo Park, Kwon-Yul Ryu
1. Ubiquitin homeostasis: from neural stem cell differentiation to neuronal development
Han-Wook Ryu, Kwon-Yul Ryu