Research Project

지원기관
한국연구재단 (과학기술정보통신부)
사업명/역할
중견연구 / 연구책임
수행년도
2023-03-01 ~ 2028-02-29
과제명
성상세포 분비단백질 리포칼린-2 레벨 조절 및 성상세포 활성화 유형 변화를 통한 신경세포 생존력 강화 모델 구축

대표 성과물

논문
5. A potential link between early onset reactive astrogliosis and adult-onset dysfunction of leptin signaling in polyubiquitin gene Ubb knockout mice
Jin-Sil Bae,Sekee Yoon,Taek-Yeong Kim, Kwon-Yul Ryu
Discovery Medicine , 2025 , 37(195) , 737–749 , Link
4. Lipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis
Byung-Kwon Jung, Kwon-Yul Ryu
Experimental & Molecular Medicine , 2023 , 55(10) , 2138–2146 , Link
3. Proteasome inhibition suppresses the induction of lipocalin-2 upon systemic lipopolysaccharide challenge in mice
Jin-Sil Bae, Ji-Eun Heo, Kwon-Yul Ryu
Molecular Brain , 2024 , 17(1) , 73 , Link
2. Signal peptide-directed proteins generated in the endoplasmic reticulum are secreted or degraded via the autophagic pathway
Taek-Yeong Kim, Ye-Jin Cho, Kwon-Yul Ryu
Biochimica et Biophysica Acta – Molecular Cell Research , 2026 , 1873(4) , 120140 , Link
1. Transdermal drug delivery system using light and moisture dual responsive hybrid microneedles
Hwanju Jeong, Hakchun Kim, Jin-Sil Bae, Gayoung Lee, Seungyeon Han, Yuna Han, Erica E. Jung, Kwon-Yul Ryu, Yun Jung Heo, Inhee Choi
BioChip Journal , 2025 , 19(1) , 62–78 , Link
특허
LCN2 저해제를 유효성분으로 포함하는 신경퇴행성 질환 예방 또는 치료용 조성물
유권열, 정병권
10-2023-0054370, 대한민국, 2023-04-25