Department of Life Science, UOS

세미나

Department of Life Science, UOS

[정기세미나] 2024학년도 1학기 생명과학과 5차 세미나

  • -연사 : 김두리 교수 (한양대학교 화학과)
  • -연제 : Ultrasturctural Studies of Gram-positive Bacteria and Their Extracellular Vesicles
  • -일시 : 2024.04.29 (월) 10:30 ~
  • -장소 : 시대융합관-B12호
 첨부파일 (2개)
The past decade has witnessed the development of super-resolution microscopy (SRM), a research field recognized with the Nobel Prize in Chemistry in 2014, which overcomes the diffraction-based far-field resolution limits of conventional light microscopy. The new opportunities afforded by SRM have motivated extensive research, providing multidimensional, multi-scale, and corroborated information about a system's morphology, functionality, dynamics, cellular context, and chemical composition. In this presentation, I will introduce our technology development and recent applications of the SRM technique. In particular, I will present our recent studies on the biogenesis of extracellular vesicles (EVs) in gram-positive bacteria and their direct interaction with human host cells. Bacterial EVs are known to play a role in bacterial communication and the transfer of genetic material, and they are being studied as potential diagnostic markers and therapeutic targets for bacterial infections. We observed bacterial EV formation and their host cell infection in super-resolution to investigate the biological roles of EVs. These findings call for a reassessment of previously unresolved, complex, and multi-factorial biological processes involving nano-sized EV.s
 첨부파일 (2개)