[대학원] 서울시립대 생명과학과 한승연 석사, 안현지 석사 Nano Letters 논문 게재 및 한빛사 소개
한승연 석사와 안현지 석사(現하버드메디컬스쿨 박사과정)가 공동 제1저자로 Nano Letters (IF: 10.8) 2024년 2월호에 "PlasmonicOpticalWells-BasedEnhancedRatePCR" 주제로 논문을 게재하고 한빛사에 소개되었습니다.
이 연구에는 김미설 (학부 연구원) 도 공동저자로 참여하였습니다.
축하합니다!!!
출처: https://pubs.acs.org/doi/epdf/10.1021/acs.nanolett.3c04615
출처: https://www.ibric.org/bric/hanbitsa/treatise.do?mode=treatise-view&id=92319&authorId=44697#!/list
이 연구에는 김미설 (학부 연구원) 도 공동저자로 참여하였습니다.
축하합니다!!!
출처: https://pubs.acs.org/doi/epdf/10.1021/acs.nanolett.3c04615
Nano Lett., Jan 29 2024, | https://doi.org/10.1021/acs.nanolett.3c04615Plasmonic Optical Wells-Based Enhanced Rate PCR
Authors and Affiliations
Abstract
Rapid, sensitive, inexpensive point-of-care molecular diagnostics are crucial for the efficient control of spreading viral diseases and biosecurity of global health. However, the gold standard, polymerase chain reaction (PCR) is time-consuming and expensive and needs specialized testing laboratories. Here, we report a low-cost yet fast, selective, and sensitive Plasmonic Optical Wells-Based Enhanced Rate PCR: POWER-PCR. We optimized the efficient optofluidic design of 3D plasmonic optical wells via the computational simulation of light-to-heat conversion and thermophoretic convection in a self-created plasmonic cavity. The POWER-PCR chamber with a self-passivation layer can concentrate incident light to accumulate molecules, generate rapid heat transfer and thermophoretic flow, and minimize the quenching effect on the naked Au surface. Notably, we achieved swift photothermal cycling of nucleic acid amplification in POWER-PCR on-a-chip in 4 min 24 s. The POWER-PCR will provide an excellent solution for affordable and sensitive molecular diagnostics for precision medicine and preventive global healthcare.
논문정보
- 형식Research article
- 게재일2024년 01월 (BRIC 등록일 2024-02-01)
- 연구진국내(교신)+국외 연구진
- 분야 바이오·의료융합 > 바이오센싱 및 나노바이오물질
출처: https://www.ibric.org/bric/hanbitsa/treatise.do?mode=treatise-view&id=92319&authorId=44697#!/list
