23. Sphingosine-1-phosphate receptor 1 signaling stimulates human pluripotent stem cell-derived cardiomyocyte differentiation and maturation.
Won Dong Yu, Seul-Gi Lee, Kwang Bo Jung, Sung-Ae Hyun, Young-Dae Kim, Ye Seul Son, Hana Lee, Hyun-Soo Cho, Dae-Soo Kim, Kyung Jin Lee, Jongman Yoo, C-Yoon Kim, Mi-Ok Lee, Ohman Kwon, Mi-Young Son
Experimental & molecular medicine
, 2026
, Link
22. Drug-induced gastrointestinal toxicity and barrier integrity: cytoskeleton-mediated impairment in a clinically relevant human intestinal epithelium model.
Won Dong Yu, Sugi Lee, Hyun-Soo Cho, Ohman Kwon, Jung Hwa Lim, Cho-Rok Jung, Byunghyun Jang, Kyung Jin Lee, Jongman Yoo, Dae-Soo Kim, Hana Lee, Mi-Young Son
21. Tailored Xenogeneic-Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells.
Seonghyeon Park, Sang Yu Sun, Jin Gyeong Son, Sun Young Lee, Hyun Kyong Shon, Ohman Kwon, Minseok Lee, Keonwoo Choi, Jemin Yeun, Sung Hyun Yoon, Minkyung Kim, Mi-Young Son, Tae Geol Lee, Sung Gap Im
20. Helicobacter pylori VacA-induced mitochondrial damage in the gastric pit cells of the antrum and therapeutic rescue.
Ye Seul Son, Yong Hwan Kwon, Moo-Seung Lee, Ohman Kwon, Yu-Jin Jeong, Seon Ju Mun, Sojeong Jeon, Ji Hye Park, Man-Hoon Han, Jae-Sung Bae, Keun Hur, Ah-Ra Jang, Jong-Hwan Park, Hyun-Soo Cho, Cho-Rok Jung, Choong-Min Ryu, Myung Jin Son, Doo-Sang Park, Mi-Young Son
19. Xenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy.
Seonghyeon Park, Ohman Kwon, Hana Lee, Younghak Cho, Jemin Yeun, Sung Hyun Yoon, Sang Yu Sun, Yubin Huh, Won Dong Yu, Sohee Park, Naeun Son, Sojeong Jeon, Sugi Lee, Dae-Soo Kim, Sun Young Lee, Jin Gyeong Son, Kyung Jin Lee, Yong Il Kim, Jin Hong Lim, Jongman Yoo, Tae Geol Lee, Mi-Young Son, Sung Gap
18. Long-Term Culture of Human Pluripotent Stem Cells in Xeno-Free Condition Using Functional Polymer Films.
Younghak Cho, Hana Lee, Wonji Jeong, Kwang Bo Jung, Sun Young Lee, Seonghyeon Park, Jemin Yeun, Ohman Kwon, Jin Gyeong Son, Tae Geol Lee, Mi-Young Son, Sung Gap Im
17. Chemically-defined and scalable culture system for intestinal stem cells derived from human intestinal organoids.
Ohman Kwon, Hana Lee, Jaeeun Jung, Ye Seul Son, Sojeong Jeon, Won Dong Yu, Naeun Son, Kwang Bo Jung, Eunho Choi, In-Chul Lee, Hyung-Jun Kwon, Chuna Kim, Mi-Ok Lee, Hyun-Soo Cho, Dae Soo Kim, Mi-Young Son
16. Generation of Highly Expandable Intestinal Spheroids Composed of Stem Cells.
Ohman Kwon, Won Dong Yu, Ye Seul Son, Kwang Bo Jung, Hana Lee, Mi-Young Son
15. Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant mice.
Hana Lee, Kwang Bo Jung, Ohman Kwon, Ye Seul Son, Eunho Choi, Won Dong Yu, Naeun Son, Jun Hyoung Jeon, Hana Jo, Haneol Yang, Yeong Rak Son, Chan-Seok Yun, Hyun-Soo Cho, Sang Kyu Kim, Dae-Soo Kim, Doo-Sang Park, Mi-Young Son
14. Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells.
Bokyeong Ryu, Mi-Young Son, Kwang Bo Jung, Ukjin Kim, Jin Kim, Ohman Kwon, Ye Seul Son, Cho-Rok Jung, Jae-Hak Park, C-Yoon Kim
13. Impedance Measurement System for Assessing the Barrier Integrity of Three-Dimensional Human Intestinal Organoids.
Jaehwan Ahn, Kwang Bo Jung, Ohman Kwon, Mi-Sun Choi, Jun-Ho Ahn, Hyoung-Yun Han, Cho-Rok Jung, Seokjoo Yoon, Mi-Young Son, Jung-Hwa Oh
Analytical chemistry
, 2021
, Link
12. The development of a functional human small intestinal epithelium model for drug absorption.
Ohman Kwon, Kwang Bo Jung, Kyeong-Ryoon Lee, Ye Seul Son, Hana Lee, Jong-Jin Kim, Kwangho Kim, Seop Lee, Yoo-Kyung Song, Jaeeun Jung, Kunhyang Park, Dae-Soo Kim, Myung Jin Son, Mi-Ok Lee, Tae-Su Han, Hyun-Soo Cho, Soo Jin Oh, Haeun Chung, Sang-Heon Kim, Kyung-Sook Chung, Janghwan Kim, Cho-Rok Jung,
11. Intestinal Morphogenesis in Development, Regeneration, and Disease: The Potential Utility of Intestinal Organoids for Studying Compartmentalization of the Crypt-Villus Structure.
Ohman Kwon, Tae-Su Han, Mi-Young Son
10. Low-dose interleukin-2 alleviates dextran sodium sulfate-induced colitis in mice by recovering intestinal integrity and inhibiting AKT-dependent pathways.
Hana Lee, Ye Seul Son, Mi-Ok Lee, Jea-Woon Ryu, Kunhyang Park, Ohman Kwon, Kwang Bo Jung, Kwangho Kim, Tae Young Ryu, Aruem Baek, Janghwan Kim, Cho-Rok Jung, Choong-Min Ryu, Young-Jun Park, Tae-Su Han, Dae-Soo Kim, Hyun-Soo Cho, Mi-Young Son
9. Propionate of a microbiota metabolite induces cell apoptosis and cell cycle arrest in lung cancer.
Kwangkho Kim, Ohman Kwon, Tae Young Ryu, Cho-Rok Jung, Janghwan Kim, Jeong-Ki Min, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
8. Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells.
Kwang Bo Jung, Ohman Kwon, Mi-Ok Lee, Hana Lee, Ye Seul Son, Omer Habib, Jung-Hwa Oh, Hyun-Soo Cho, Cho-Rok Jung, Janghwan Kim, Mi-Young Son
7. A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model.
Ye Seul Son, Kwangman Choi, Hana Lee, Ohman Kwon, Kwang Bo Jung, Sunwha Cho, Jiyeon Baek, Bora Son, Sung-Min Kang, Mingu Kang, Jihee Yoon, Haihong Shen, Sangku Lee, Jung-Hwa Oh, Hyang-Ae Lee, Mi-Ok Lee, Hyun-Soo Cho, Cho-Rok Jung, Janghwan Kim, Sungchan Cho, Mi-Young Son
6. Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids.
Kwang Bo Jung, Hana Lee, Ye Seul Son, Mi-Ok Lee, Young-Dae Kim, Soo Jin Oh, Ohman Kwon, Sunwha Cho, Hyun-Soo Cho, Dae-Soo Kim, Jung-Hwa Oh, Matthias Zilbauer, Jeong-Ki Min, Cho-Rok Jung, Janghwan Kim, Mi-Young Son
5. Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization.
Ohman Kwon, Dongoh Kwak, Sang Hoon Ha, Hyeona Jeon, Mangeun Park, Yeonho Chang, Pann-Ghill Suh, Sung Ho Ryu
4. Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition.
Dohyun Park, Heeyoon Jeong, Mi Nam Lee, Ara Koh, Ohman Kwon, Yong Ryoul Yang, Jungeun Noh, Pann-Ghill Suh, Hwangseo Park, Sung Ho Ryu
3. Spiraeoside inhibits mast cells activation and IgE-mediated allergic responses by suppressing phospholipase C-γ-mediated signaling.
Jung Kuk Kim, Young-Kyo Seo, Sehoon Park, Soo-Ah Park, Seyoung Lim, Susie Lee, Ohman Kwon, Jeong Kon Seo, Ung-Kyu Choi, Sung Ho Ryu, Pann-Ghill Suh
2. PDZ domain-containing 1 (PDZK1) protein regulates phospholipase C-β3 (PLC-β3)-specific activation of somatostatin by forming a ternary complex with PLC-β3 and somatostatin receptors.
Jung Kuk Kim, Ohman Kwon, Jinho Kim, Eung-Kyun Kim, Hye Kyung Park, Ji Eun Lee, Kyung Lock Kim, Jung Woong Choi, Seyoung Lim, Heon Seok, Whaseon Lee-Kwon, Jang Hyun Choi, Byoung Heon Kang, Sanguk Kim, Sung Ho Ryu, Pann-Ghill Suh
1. Phospholipase C-η1 is activated by intracellular Ca(2+) mobilization and enhances GPCRs/PLC/Ca(2+) signaling.
Jung Kuk Kim, Jung Woong Choi, Seyoung Lim, Ohman Kwon, Jeong Kon Seo, Sung Ho Ryu, Pann-Ghill Suh
