신호전달네트워크 실험실

Signaling Network Laboratory

신호전달네트워크 실험실

Signaling Network Laboratory

Welcome to Signaling Network Laboratory

Our lab is focused on elucidating two fundamental principles in biology. 1. Exploring organ size control, homeostasis, and cancer development. 2. Investigating Transcription Factor Condensate Formation and Functions. Through our research efforts in these areas, we aim to advance our understanding of organ size regulation, homeostasis, transcription factor condensates, and their implications in disease development.

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Exploring structural and biological insights of TEAD through rational design and synthesis of niflumic acid derivatives
Yong-Sung Choi, Yoon-Jung Kim, Yeram Jeon, Jong Soon Kang, Juhee Lee, Eunmi Hong, Young-Hoon Park, Wantae Kim, Boksik Cha & Raok Jeon
Journal of Enzyme Inhibition and Medicinal Chemistry, 2024, Link
The TOX-RAGE axis mediates inflammatory activation and lung injury in severe pulmonary infectious diseases
Hyelim Kim , Hee Ho Park, Hong Nam Kim, Donghyuk Seo, Kyung Soo Hong, Jong Geol Jang, Eun U Seo, In-Young Kim, So-Young Jeon, Boram Son, Seong-Woo Cho, Wantae Kim, June Hong Ahn, Wonhwa Lee
Proc Natl Acad Sci U S A, 2024, 121:e2319322121 Link