2023
2. Cyclin Y regulates spatial learning and memory flexibility through distinct control of the actin pathway
Jiyeon Seo, Hongik Hwang, Heesung Sohn, Eunsil Cho, Sunmin Jung, Soohyun Kim, Seung Min Um, Ji Yeon Kim, Muwon Kang, Yuri Choi, Jong-Hwan Kim, Mirang Kim, Seon-Young Kim, Sun-Kyung Lee, Joohong Ahnn, Hyewhon Rhim, Dong-Gyu Jo, Eunjoon Kim, Mikyoung Park
1. Preparation of Red Ginseng Marc-Derived Gintonin and Its Application as a Skin Nutrient
Rami Lee, Ji-Hun Kim, Hongik Hwang, Hyewhon Rhim, Sung-Hee Hwang, Ik-Hyun Cho, Do-Geun Kim, Hyoung-Chun Kim, Seung-Yeol Nah
2022
3. Visualization of the binding between gintonin, a Panax ginseng-derived LPA receptor ligand, and the LPA receptor subtypes and transactivation of the EGF receptor
Sun-Hye Choi, Ra Mi Lee, Han-Sung Cho, Sung Hee Hwang, Hong-Ik Hwang, Hyewhon Rhim, Hyoung-Chun Kim, Do-Geun Kim, Ik-Hyun Cho, Seung-Yeol Nah
2. Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer's Disease
Md Ataur Rahman, M D Hasanur Rahman, A N M Mamun-Or-Rashid, Hongik Hwang, Sooyoung Chung, Bonglee Kim, Hyewhon Rhim
1. Myristoylation-dependent palmitoylation of cyclin Y modulates long-term potentiation and spatial learning
Jiyeon Seo, Hongik Hwang, Yuri Choi, Sunmin Jung, Jung-Hwa Hong, Bong-June Yoon, Hyewhon Rhim, Mikyoung Park
2021
5. Cyclin Y, a novel actin-binding protein, regulates spine plasticity through the cofilin-actin pathway
Hongik Hwang, Young-Na Hur, Heesung Sohn, Jiyeon Seo, Jung-Hwa Hong, Eunsil Cho, Yuri Choi, Saebom Lee, Seongeun Song, A-Ram Lee, Suyeon Kim, Dong-Gyu Jo, Hyewhon Rhim, Mikyoung Park
4. Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome
Hongik Hwang, Matthew J Szucs, Lei J Ding, Andrew Allen, Xiaobai Ren, Henny Haensgen, Fan Gao, Hyewhon Rhim, Arturo Andrade, Jen Q Pan, Steven A Carr, Rushdy Ahmad, Weifeng Xu
3. Central administration of afzelin extracted from Ribes fasciculatum improves cognitive and memory function in a mouse model of dementia
So-Young Oh, Min Jun Jang, Yun-Hyeok Choi, Hongik Hwang, Hyewhon Rhim, Bonggi Lee, Chun Whan Choi, Min Soo Kim
2. Effect of the Gintonin-Enriched Fraction on Glucagon-Like-Protein-1 Release
Rami Lee, Sun-Hye Choi, Han-Sung Cho, Hongik Hwang, Hyewhon Rhim, Hyoung-Chun Kim, Sung-Hee Hwang, Seung-Yeol Nah
1. Hypothalamic administration of sargahydroquinoic acid elevates peripheral thermogenic signaling and ameliorates high fat diet-induced obesity through the sympathetic nervous system
Doyeon Kim, Yuna Lee, Hyeung-Rak Kim, Yeo Jin Park, Hongik Hwang, Hyewhon Rhim, Taek Kang, Chun Whan Choi, Bonggi Lee, Min Soo Kim
2020
8. Effects of a gintonin-enriched fraction on hair growth: an in vitro and in vivo study
Na-Eun Lee, Sang-Deuk Park, Hongik Hwang, Sun-Hye Choi, Ra Mi Lee, Sung Min Nam, Jong Hee Choi, Hyewhon Rhim, Ik-Hyun Cho, Hyoung-Chun Kim, Sung-Hee Hwang, Seung-Yeol Nah
7. Ginseng Gintonin Contains Ligands for GPR40 and GPR55
Yeon-Jin Cho, Sun-Hye Choi, Rami Lee, Hongik Hwang, Hyewhon Rhim, Ik-Hyun Cho, Hyoung-Chun Kim, Jeong-Ik Lee, Sung-Hee Hwang, Seung-Yeol Nah
6. Gintonin stimulates autophagic flux in primary cortical astrocytes
Md Ataur Rahman, Hongik Hwang, Seung-Yeol Nah, Hyewhon Rhim
5. Elevated O-GlcNAcylation induces an antidepressant-like phenotype and decreased inhibitory transmission in medial prefrontal cortex
Yoonjeong Cho, Hongik Hwang, Md Ataur Rahman, ChiHye Chung, Hyewhon Rhim
4. Ginsenoside Rk1 is a novel inhibitor of NMDA receptors in cultured rat hippocampal neurons
Nayeon Ryoo, Md Ataur Rahman, Hongik Hwang, Sung Kwon Ko, Seung-Yeol Nah, Hyoung-Chun Kim, Hyewhon Rhim
3. Ccny knockout mice display an enhanced susceptibility to kainic acid-induced epilepsy
Hongik Hwang, Jiyeon Seo, Yuri Choi, Eunsil Cho, Heesung Sohn, Jaewon Jang, A-Ram Lee, Jiyoung Lee, Suyeon Kim, Hae-Young Koh, Mikyoung Park
2. Pharmacological Inhibition of O-GlcNAc Transferase Promotes mTOR-Dependent Autophagy in Rat Cortical Neurons
Md Ataur Rahman, Yoonjeong Cho, Hongik Hwang, Hyewhon Rhim
1. Modulatory Effects of Autophagy on APP Processing as a Potential Treatment Target for Alzheimer's Disease
Md Ataur Rahman, Md Saidur Rahman, M D Hasanur Rahman, Mohammad Rasheduzzaman, Anm Mamun-Or-Rashid, Md Jamal Uddin, Md Rezanur Rahman, Hongik Hwang, Myung-Geol Pang, Hyewhon Rhim
2019
7. Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway
Min Gi Jo, Muhammad Ikram, Myeung Hoon Jo, Lang Yoo, Kwang Chul Chung, Seung-Yeol Nah, Hongik Hwang, Hyewhon Rhim, Myeong Ok Kim
6. Gintonin, a Ginseng-Derived Exogenous Lysophosphatidic Acid Receptor Ligand, Protects Astrocytes from Hypoxic and Re-oxygenation Stresses Through Stimulation of Astrocytic Glycogenolysis
Sun-Hye Choi, Hyeon-Joong Kim, Hee-Jung Cho, Sang-Deuk Park, Na-Eun Lee, Sung-Hee Hwang, Ik-Hyun Cho, Hongik Hwang, Hyewhon Rhim, Hyoung-Chun Kim, Seung-Yeol Nah
5. Physical and Functional Interaction between 5-HT6 Receptor and Nova-1
Soon-Hee Kim, Misun Seo, Hongik Hwang, Dong-Min Moon, Gi Hoon Son, Kyungjin Kim, Hyewhon Rhim
4. Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors
Hongik Hwang, Hyewhon Rhim
3. Deletion of PLCγ1 in GABAergic neurons increases seizure susceptibility in aged mice
Hye Yun Kim, Yong Ryoul Yang, Hongik Hwang, Ha-Eun Lee, Hyun-Jun Jang, Jeongyeon Kim, Esther Yang, Hyun Kim, Hyewhon Rhim, Pann-Ghill Suh, Jae-Ick Kim
2. Ginseng Gintonin Enhances Hyaluronic Acid and Collagen Release from Human Dermal Fibroblasts Through Lysophosphatidic Acid Receptor Interaction
Rami Lee, Na-Eun Lee, Hongik Hwang, Hyewhon Rhim, Ik-Hyun Cho, Seung-Yeol Nah
1. Modulation of O-GlcNAcylation Regulates Autophagy in Cortical Astrocytes
Md Ataur Rahman, Hongik Hwang, Yoonjeong Cho, Hyewhon Rhim
2018
4. Functional significance of O-GlcNAc modification in regulating neuronal properties
Hongik Hwang, Hyewhon Rhim
3. Rapid, experience-dependent translation of neurogranin enables memory encoding
Kendrick J Jones, Sebastian Templet, Khaled Zemoura, Bozena Kuzniewska, Franciso X Pena, Hongik Hwang, Ding J Lei, Henny Haensgen, Shannon Nguyen, Christopher Saenz, Michael Lewis, Magdalena Dziembowska, Weifeng Xu
2. SAP102 regulates synaptic AMPAR function through a CNIH-2-dependent mechanism
Mingna Liu, Rebecca Shi, Hongik Hwang, Kyung Seok Han, Man Ho Wong, Xiaobai Ren, Laura D Lewis, Emery N Brown, Weifeng Xu
1. Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions
Sung Min Nam, Hongik Hwang, Misun Seo, Byung-Joon Chang, Hyeon-Joong Kim, Sun-Hye Choi, Hyewhon Rhim, Hyoung-Chun Kim, Ik-Hyun Cho, Seung-Yeol Nah
2017
2. Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation
Yong Ryoul Yang, Seungju Song, Hongik Hwang, Jung Hoon Jung, Su-Jeong Kim, Sora Yoon, Jin-Hoe Hur, Jae-Il Park, Cheol Lee, Dougu Nam, Young-Kyo Seo, Joung-Hun Kim, Hyewhon Rhim, Pann-Ghill Suh
1. Shank Proteins Differentially Regulate Synaptic Transmission
Rebecca Shi, Patrick Redman, Dipanwita Ghose, Hongik Hwang, Yan Liu, Xiaobai Ren, Lei J Ding, Mingna Liu, Kendrick J Jones, Weifeng Xu
2010
1. A specific requirement of Arc/Arg3.1 for visual experience-induced homeostatic synaptic plasticity in mouse primary visual cortex
Ming Gao, Kenneth Sossa, Lihua Song, Lauren Errington, Laurel Cummings, Hongik Hwang, Dietmar Kuhl, Paul Worley, Hey-Kyoung Lee
2009
1. Synapse- and stimulus-specific local translation during long-term neuronal plasticity
Dan Ohtan Wang, Sang Mok Kim, Yali Zhao, Hongik Hwang, Satoru K Miura, Wayne S Sossin, Kelsey C Martin
