63. Synergistic effect of Aloe vera flower and Aloe gel on cutaneous wound healing targeting MFAP4 and its associated signaling pathway: In-vitro study
Sultana Razia, Hyunsung Park, Eunju Shin, Kyu-Suk Shim, Eunae Cho, Min Chol Kang, Sun Yeou Kim
62. Gold and Silver plasmonic nanoprobes trace the position of histone codes
Inhee Choi Jiwhan Song, and Hyunsung Park
61. Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
Yunwon Moon, Sehyun Chae, Sujin Yim, Eun Gyeong Yang, Jungwoo Choe, Jiyeon Hyun, Rakwoo Chang, Daehee Hwang, Hyunsung Park
60. YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity
Gwan-Jun Lee, Youn Ju Kim, Bongju Park, Sujin Yim, Chansang Park, Hyunsoo Roh, Yunwon Moon, Je Kyung Seong, Hyunsung Park
59. High-spatial and colourimetric imaging of histone modifications in single senescent cells using plasmonic nanoprobes
Hyun Ji An, Yun Kim, Soojeong Chang, Hakchun Kim, Jihwan Song, Hyunsung Park, Inhee Choi
58. Effects of Aloe vera Flower Extract and Its Active Constituent Isoorientin on Skin Moisturization via Regulating Involucrin Expression: In Vitro and Molecular Docking Studies
Sultana Razia, Hyunsung Park, Eunju Shin, Kyu-Suk Shim, Eunae Cho and Sun-Yeou Kim
57. Hypoxia-Driven HIF-1α Activation Reprograms Pre-Activated NK Cells towards Highly Potent Effector Phenotypes via ERK/STAT3 Pathways
Seon Ah Lim, Yunwon Moon, Min Hwa Shin, Tae-Jin Kim, Sehyun Chae, Cassian Yee, Daehee Hwang, Hyunsung Park, Kyung-Mi Lee
56. Hypoxia regulates allele-specific histone modification of the imprinted H19 gene
Yunwon Moon, Ingyum Kim, Seongyeol Lee, Soojeong Chang, Bongju Park, Seongwook Yoo, Sehyun Chae, Daehee Hwang, Hyunsung Park
55. HIF-1α-dependent Induction of Carboxypeptidase A4 and Carboxypeptidase E in Hypoxic Human Adipose-derived Stem Cells
Yunwon Moon, Ramhee Moon, Hyunsoo Roh, Soojeong Chang, Seongyeol Lee, Hyunsung Park
54. The Cancer driver genes, IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: Crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism
Soojeong Chang, Sujin Yim & Hyunsung Park
53. Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis
Bongju Park, Soojeong Chang, Gwan-Jun Lee, Byeongsoo Kang, Jong Kyoung Kim & Hyunsung Park
52. Distinct hypoxic regulation of preadipocyte factor-1 (Pref-1) in preadipocytes and mature adipocytes
Yunwon Moon, Seongyeol Lee, Bongju Park, Hyunsung Park
51. Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia
Seongyeol Lee, Jieon Lee, Sehyun Chae, Yunwon Moon, Ho-Youl Lee, Bongju Park, Eun Gyeong Yang, Daehee Hwang, Hyunsung Park
50. Hypoxia suffocates histone demethylases to change gene expression: a metabolic control of histone methylation
Hyunsung Park
49. Hypoxic reprograming of H3K27me3 and H3K4me3 at the INK4A locus
Soojeong Chang, Bongju Park, Kang Choi, Yunwon Moon, Ho-Youl Lee, Hyunsung Park
48. New ethanol extraction improves the anti-obesity effects of black tea
Bongju Park, Sangjin Lee, Bonggyeong Lee, Ingyum Kim, Namjoon Baek, Tae Ho Lee, Seok-Yong Lee, Miwon Son, Hyunsung Park
47. Hypoxic repression of CYP7A1 through a HIF-1a- and SHP-independent mechanism
Yunwon Moon, Bongju Park, Hyunsung Park
46. Improved quantification of protein in vaccines containing aluminum hydroxide by simple modificImproved quantificatation of the Lowry method
Naery Lee, SukJin Shin, Hye Joo Chung, Do Keun Kim, Jong-Mi Lim, Hyunsung Park, Ho Jung Oh
45. The actions of HIF-3alpha variants on HIF-2alpha and HIF-1beta heterodimer formation is directly probed in live cells
Seong Ho Kim, Dohyeon Hwang, Hyunsung Park, Eun Gyeong Yang, Hak Suk Chung, So Yeon Kim
44. Chenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes
Yunwon Moon, Su Mi Choi, Soojeong Chang, Bongju Park, Seongyeol Lee, Mi-Ock Lee, Hueng-Sik Choi, Hyunsung Park
43. Beta-lapachone inhibits pathological retinal neovascularization in oxygen-induced retinopathy via regulation of HIF-1α
Sung Wook Park, Jin Hyoung Kim, Ko-Eun Kim, Moon Hee Jeong, Hyunsung Park, Bongju Park, Young-Ger Suh, Woo Jin Park, Jeong Hun Kim
42. HIF-1-Dependent Induction of Jumonji Domain-Containing Protein (JMJD) 3 under Hypoxic Conditions
Ho-Youl Lee, Kang Choi, Hookeun Oh, Young-Kwon Park, Hyunsung Park
41. Hypoxia enhances the expression of Prostate Specific Antigen by modifying the quantity and catalytic activity of Jumonji C domain-containing histone demethylases
Ho-Youl Lee, Eun Gyeong Yang, Hyunsung Park
40. Hypoxia-Inducible Factor-2a-Dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells
Young-Kwon Park, Bongju Park, Seongyeol Lee, Kang Choi, Yunwon Moon, Hyunsung Park
39. Menadione and ethacrynic acid inhibit the hypoxia-inducible factor (HIF) pathway by disrupting HIF-1α interaction with p300
Yu-Ran Na, Ki-Cheol Han, Hyunsung Park, Eun Gyeong Yang
38. Effects of clioquinol analogues on the hypoxia-inducible factor pathway and intracelullar mobilization of metal ions
So Yeon Kim, Myong Jin Lee, Jeong Won Kim, Yu-Ran Na, Ho-Youl Lee, Hyunju Cho, Keun Byeol Lee, You Mie Lee, Cheolju Lee, Hyunsung Park, Eun Gyeong Yang
37. Differentiated embryo chondrocyte 1 (DEC1) represses PPARg2 gene through interacting with CCAAT/Enhancer binding protein β (C/EBPβ)
Young-Kwon Park, Hyunsung Park
36. Src activates HIF-1a not through direct phosphorylation of HIF-1a-specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway
Ho-Youl Lee, Taekyong Lee, Naery Lee, Eun G Yang, Cheolju Lee, Jonghyun Lee, Eun-Yi Moon, Joohun Ha, Hyunsung Park
35. Estrogen Receptor Beta Inhibits Transcriptional Activity of Hypoxia Inducible Factor-1 through the Downregulation of Arylhydrocarbon Receptor Nuclear Translocator
Wonchung Lim, Yeomyung Park, Jungyoon Cho, Choa Park, Joonwoo Park, Young-Kwon Park, Hyunsung Park, Youngjoo Lee
34. Crystal structures of human FIH-1 in complex with quinol family inhibitors
Hyunjin Moon, Sojung Han, Hyunsung Park, Jungwoo Choe
33. Prevention of CCAAT/enhancer binding protein β DNA binding by hypoxia during adipogenesis
Young-Kwon Park, Hyunsung Park
32. The novel peptide F29 facilitates the DNA-binding ability of hypoxia-inducible factor-1alpha
Su Mi Choi & Hyunsung Park
31. Microarray analyses of hypoxia-regulated genes in Aryl hydrocarbon receptor nuclear translocator (Arnt)-dependent manner
Su Mi Choi, Hookeun Oh, Hyunsung Park
30. Stra13/DEC1 and DEC2 Inhibit Sterol Regulatory Element Binding Protein-1c In a Hypoxia-Inducible Factor-Dependent Mechanism.
Su Mi Choi, Hyun-Ju Cho, Heesang Cho, Kang Ho Kim, Jae Bum Kim, Hyunsung Park
29. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
Young-Kwon Park, Dae-Ro Ahn, Myoungsuk Oh, Taekyoung Lee, Eun Gyeong Yang, Miwon Son, Hyunsung Park
28. Baicalein Induces Functional Hypoxia-Inducible Factor-1α and Angiogenesis
Hyunju Cho, Ho-Youl Lee, Dae-Ro Ahn, Sang Yoon Kim, Sunyun Kim, Keun Byeol Lee, You Mie Lee, Hyunsung Park and Eun Gyeong Yang
27. Novel Dioxygenases, HIF-α Specific Prolyl-hydroxylase and Asparaginyl-hydroxylase: O2 Switch for Cell Survival
Hyunsung Park
26. Reactive Oxygen Species Stabilize Hypoxia Inducible Factor-1 Alpha Protein and Stimulate Transcriptional Activity via AMP-activated Protein Kinase in DU145 Human Prostate Cancer Cells
Seung-Nam Jung, Woo Kyeom Yang, Joungmok Kim, Hak Su Kim, Eun Ju Kim, Hee Yun, Hyunsung Park, Sung Soo Kim, Wonchae Choe, Insug Kang, Joohun Ha
25. Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells
Hwa Jung Choi, Jae-Soon Eun, Dae Keun Kim, Ri Hua Li, Tae-Yong Shin, Hyunsung Park, Nam-Pyo Cho, Yunjo Soh
24. B cell activating factor (BAFF) gene promoter activity depends upon co-activator, p300
Eun-Yi Moon, Hyunsung Park
23. Modulation of p300 binding by posttranslational modification of the C-terminal activation domain of hypoxia-inducible factor-1α
Hyunju Cho, Dae-Ro Ahn, Hyunsung Park, Eun Gyeong Yang
22. Clioquinol, a Cu(II)/Zn(II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1alpha, leading to expression of vascular endothelial growth factor and erythropoietin in normoxic cells
Su Mi Choi, Kyung-Ok Choi, Young-Kwon Park, Hyunju Cho, Eun Gyeong Yang, Hyunsung Park
21. The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1α protein in normoxic cells
Su Mi Choi, Kyung-Ok Choi, Naery Lee, Myoungsuk Oh, Hyunsung Park
20. Aryl Hydrocarbon Receptor Nuclear Translocator is involved in ATP Homeostasis in both normoxic and hypoxic monolayer mouse hepatoma cells
Su Mi Choi and Hyunsung Park
19. Inhibition of the catalytic activity of HIF-1-prolyl hydroxylase 2 by a MYND-type zinc finger
Kyung-Ok Choi, Taekyong Lee, Naery Lee, Ji-Hyun Kim, Eun Gyeong Yang, Jung Min Yoon, Jin Hwan Kim, Tae Gyu Lee, Hyunsung Park
18. A fluorescence polarization-based interaction assay for hypoxia-inducible factor prolyl hydroxylases
Hyunju Cho, Hyunsung Park, Eun Gyeong Yang
17. Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner
Kang Ho Kim, Min Jeong Song, Jieun Chung, Hyunsung Park, Jae Bum Kim
16. Novel Function of Orphan Nuclear Receptor Nur77 in Stabilizing Hypoxia-inducible Factor-1α
Young-Gun Yoo, Myeong Goo Yeo, Dae Kyong Kim, Hyunsung Park, Mi-Ock Lee
15. Inhibition of the MEK-1/p42 MAP Kinase Represses Inhibits Aryl Hydrocarbon Receptor-DNA Interactions
Sujin Yim, Myoungsuk Oh, Su Mi Choi, Hyunsung Park.
14. Hepatitis B virus X protein Enhances VEGF Expression through activation of Hypoxia-Inducible Factor 1-alpha
Young-Gun Yoo, Seung Hyun Oh, Eun Sook Park, Hyeseong Cho, Naery Lee, Hyunsung Park, Dae Kyong Kim, Dae-Yeul Yu, Je Kyung Seong, Mi-Ock Lee
13. Insulin and Hypoxia Share Common Target Genes but Not the Hypoxia-Inducible Factor-1α
Sujin Yim, Su Mi Choi, Youngyeon Choi, Naery Lee, Jieun Chung, Hyunsung Park
12. Reduction of Hypoxia-Induced Transcription through the Repression of Hypoxia-Inducible Factor-1α/Aryl Hydrocarbon Receptor Nuclear Translocator DNA Binding by the 90-kDa Heat-Shock Protein Inhibitor Radicicol
Eunseon Hur, Hong-Hee Kim, Su Mi Choi, Jin Hee Kim, Sujin Yim, Ho Jeong Kwon, Youngyeon Choi, Dae Kyong Kim, Mi-Ock Lee, Hyunsung Park
11. Two Transactivation Domains of Hypoxia-inducible Factor-1α Regulated by the MEK-1/p42/p44 MAPK Pathway.
Eunjung Lee, Sujin Yim, Seung-Ki Lee, Hyunsung Park
10. Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells.
Hong-Hee Kim, Shee Eun Lee, Woon Jae Chung, Youngyeon Choi, KyuBum Kwack, Si Wouk Kim, Myong Soo Kim, Hyunsung Park, Zang Hee Lee
9. Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha
Eunseon Hur, Keun Young Chang, Eunjung Lee, Seung-Ki Lee and Hyunsung Park
8. Crystallization and preliminary X-ray crystallographic analysis of bHLH domain of Aryl hydrocarbon receptor nucleus translocator
Ji-Joon Song, Mun-Kyoung Kim, Eunseon Hur, Hyunsung Park, and Soo Hyun Eom
7. Ligand and dimerization dependent transactivation capability of aromatic hydrocarbon receptor
Hyunsung Park
6. Aromatic hydrocarbon nuclear translocator as a common component for the hypoxia- and dioxin-induced gene expression
H Park
5. Induction of Drug-Metabolizing Enzymes by Dioxin
James P. Whitlock, Christine H. Chichester, Robert M. Bedgood, Steven T. Okino,Hyunsung P. Ko, Qiang Ma,Liqun Dong, Hui Li & Regina Clarkekatzenberg
4. Transactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo
Hyunsung P. Ko,Steven T. Okino, Qiang Ma &James P. Whitlock Jr.
3. Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha
Hui Li, Hyunsung P. Ko, Whitlock James P. Jr.
2. Induction of cytochrome P4501A1: a model for analyzing mammalian gene transcription
James P. Whitlock Jr., Steven T. Okino, Uqun Dong, Hyunsung P. Ko, Regina Clarke-Katzenberg, Qiang Ma, Hui Li
1. Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure
Hyunsung P. Ko, Steven T. Okino, Qiang Ma & James P. Whitlock Jr.
