Journals - Publications - 서울시립대 생명과학과 세포신호전달 실험실

1. Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling.

Jeong W, Kwon H, Park SK, Lee IS, Jho EH.

EMBO Rep. , 2024 , 25: 4033 - 4061

1. Phosphorylation of EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) is indispensable for nuclear translocation of TFEB and TFE3 during ER stress. Autophagy. 2023 Jan 31. doi: 10.1080/15548627.2023.2173900. Online ahead of print.

Thao Thi Dang, Mi-Jeong Kim, Yoon Young Lee, Hien Thi Le, Kook Hwan Kim, Somi Nam, Seung Hwa Hyun, Hong Lim Kim, Su Wol Chung, Hun Taeg Chung, Jho EH, Hiderou Yoshida, Kyoungmi Kim, Chan Young Park, Myung-Shik Lee, Sung Hoon Back.

Autophagy , 2023 , 19(7); 2111–2142

4. Regulation of Hippo signaling by metabolic pathways in cancer.

Lee U, Cho E, Jho EH.

Biochim Biophys Acta Mol Cell Res. , 2022 , 1869(4);119201

3. Past, Present, and Future Perspectives of Transcription Factor EB (TFEB): Mechanisms of regulation and association with disease.

Tan A*, Prasad R*, Lee C, and Jho EH.

Cell Death Differ. , 2022 , 29(8);14331449

2. O-GlcNAcylation: An Emerging Protein Modification Regulating the Hippo Pathway.

Kim E, Kang JG, Jho EH, Yang WH, Cho JW.

Cancers (Basel). , 2022 , 14(12):3013

1. Systemic TM4SF5 overexpression in Apc Min/+ mice promotes hepatic portal hypertension associated with fibrosis

Lee J, Kim E, Kang MK, Ryu J, Kim JE, Shin EA, Pinanga Y, Pyo KH, Lee H, Lee EH, Cho H, Cheon J, Kim W, Jho EH, Kim S, Lee JW.

BMB Rep. , 2022 , 55(12);609-614

7. SGK1 inhibition in glia ameliorates pathologies and symptoms of Parkinson's disease.

Kwon O, Song J, Yang Y, Kim S, Kim J, SeoK M, Hwang I, Yu J, Jenisha K, Maeng H, Kim J, Jho EH, Ko S, Son H, Chang M, Lee S.

EMBO Mol Med. , 2021 , 13(4);e13076

6. LGK974 suppresses lipopolysaccharide-induced endotoxemia in mice by modulating the crosstalk between the Wnt/β-catenin and NF-κB pathways.

Jang J, Song J, Lee H, Sim I, Kwon YV, Jho EH*, and Yoon Y*.

Exp Mol Med. , 2021 , 53(3);407-421

5. PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1.

Kim S, Song G, Lee T, Kim M, Kwon H, Kim J, Jeong W, Lee U, Na C, Kang S, Kim W, Seong J, and Jho EH.

Cell Death Differ. , 2021 , 28(9);2555-2570

4. TFEB Regulates Pluripotency Transcriptional Network in Mouse Embryonic Stem Cells Independent of Autophagy-lysosomal Biogenesis.

Tan A, Prasad R and Jho EH.

Cell Death Dis. , 2021 , 12(4);343

3. Role of the Hippo pathway and mechanisms for controlling cellular localization of YAP/TAZ.

Kwon H, Kim J, Jho EH.

FEBS J. , 2021 , 289(19);5798-5818

2. Regulation of the low-density lipoprotein receptor-related protein LRP6 and its association with disease: Wnt/β-catenin signaling and beyond.

Jeong W, Jho EH.

Front. Cell Dev. Biol. , 2021 , 9;714330

1. Hypermethylation of Mest promoter causes aberrant Wnt signaling in the patients of Alzheimer’s disease.

Prasad R, Jung W, Tan A, Song Y, Moon S, Shaker MR, Sun W, Lee J, Ryu H, Lim HK, and Jho EH.

Scientific Rep. , 2021 , 11(1);20075

5. O-GlcNAcylation on LATS2 disrupts the Hippo pathway by inhibiting its activity.

Kim E, Kang JG, Kang MJ, Park JH, Kim YJ, Kim Y, Kweon TH, Lee HW, Jho EH, Lee Y, Kim SI, Yi EC, Park HW, Yang WH, Cho JW.

Proc Natl Acad Sci U S A. , 2020 , 117(25):1459-14269.

4. MAML1/2 promote YAP/TAZ nuclear localization to enhance tumorigenesis.

Kim J, Kwon H, Shin YK, Song G, Lee T, Kim Y, Jeong W, Lee U, Zhang X, Nam G, Jeung HC, Kim W*, Jho EH*.

Proc Natl Acad Sci U S A. , 2020 , 117(24):13529-13540.

3. The distinct role of Tcfs and Lef1 in the self-renewal or differentiation of mouse embryonic stem cells.

Kim S, Kim H, Tan A, Song Y, Lee H, Ying QL, Jho EH.

Int J Stem Cells. , 2020 , 13(2):192-201.

2. LDL receptor-related protein LRP6 senses the level of nutrient and regulates Hippo signaling.

Jeong W, Kim S, Lee U, Zhong ZA, Savitsky M, Kwon H, Kim J, Lee T, Cho JW, Williams BO, Katanaev VL, Jho EH.

EMBO Reports , 2020 , 21(9);e50103

1. TAZ/Wnt-β-catenin/c-MYC axis regulates cystogenesis in polycystic kidney disease.

Lee EJ, Seo E, Kim JW, Nam SA, Lee JY, Jun J, Oh S, Park M, Jho E, Yoo KH, Park JH, Kim YK.

Proc Natl Acad Sci U S A. , 2020 , 117(46);29001-29012

2. Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1.

Kim W, Cho YS, Wang X, Park O, Ma X, Kim H, Gan W, Jho EH, Cha B, Jeung YJ, Zhang L, Gao B, Wei W, Jiang J, Chung KS, Yang Y.

Proc Natl Acad Sci U S A. , 2019 , 116(19):9423-9432.

1. A Concise Review of Human Brain Methylome During Aging and Neurodegenerative Diseases.

Prasad R and Jho EH.

BMB Rep. , 2019 , 52(10):577-588.

10. D-tyrosine negatively regulates melanin synthesis by competitively inhibiting tyrosinase activity.

Park J, Jung H, Kim K, Lim KM, Kim JY, Jho EH, Oh ES.

Pigment Cell Melanoma Res. , 2018 , 31(3):374-383

9. Regulation of the Hippo Signaling Pathway by Ubiquitin Modification.

Kim Y, Jho EH.

BMB Rep. , 2018 , 51(3):143-150

8. The history and regulatory mechanism of the Hippo pathway.

Kim W, Jho EH.

BMB Rep. , 2018 , 51(3):106-118.

7. Hippo signaling: Special issue of BMB Reports in 2018.

Jho EH.

BMB Rep. , 2018 , 51(3):105.

6. Ubiquitylation and degradation of Adenomatous Polyposis Coli by MKRN1 enhances Wnt/β-catenin Signalling.

Lee H, Lee E, Seo J, Jeong M, Lee S, Kim SY, Jho E, Choi CH, Chung J, Song J.

Oncogene , 2018 , 37(31):4273-4286.

5. Enhancement of neuronal differentiation by using small molecules modulating Nodal/Smad, Wnt/β-catenin, and FGF signaling.

Song Y, Lee S, Jho EH.

BBRC , 2018 , 503(1):352-358

4. Keratinocytes negatively regulate the N-cadherin levels of melanoma cells via contact-mediated calcium regulation.

Chung H, Jung H, Jho EH, Multhaupt HAB, Couchman JR, Oh ES.

BBRC , 2018 , 503(2):615-620

3. Pja2 inhibits Wnt/β-catenin signaling by reducing the level of TCF/LEF1.

Song Y, Lee S, Kim JR, Jho EH.

Int J Stem Cells. , 2018 , 11(2):242-247.

2. Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling.

Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS.

Cell Rep. , 2018 , 25(3):571-584.

1. Dual role of YAP: oncoprotein and tumor suppressor.

Jho EH.

J.Thoracic Dis. , 2018 , 10, S3895-S3898.

10. Interacting network of Hippo, Wnt/b-catenin and Notch signaling represses liver tumor formation.

Kim W, Kahn SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y.

J Clin Invest. , 2017 , 127(1):137-152

9. Osmotic stress-induced phosphorylation by NLK at Ser128 activates YAP.

Hong AW, Meng Z, Yuan HX, Plouffe SW, Moon S, Kim W, Jho EH, Guan KL.

EMBO reports. , 2017 , 18(1):72-86.

8. Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization.

Moon S, Kim W, Kim S, Kim Y, Song Y, Bilousov O, Kim J, Lee T, Cha B, Kim M, Kim H, Katanaev VL , Jho EH.

EMBO reports. , 2017 , 18(1):61-71

7. LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974, in bronchial epithelial cells

Jang J, Jung Y, Kim Y, Jho EH*, Yoon YS*.

Scientific reports , 2017 , 7:41612

6. Wip1 directly dephosphorylates NLK and increases Wnt activity during germ cell development.

Cho S, Cha B, Kwon O, Lim J, Shin D, Han D, Ishitani T, Jho EH, Fornace AJ, Cha H.

BBA-Mol. Basis of Disease , 2017 , 330:157-164.

5. Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.

Kim Y, Kim W, Song Y, Kim JR, Cho K, Moon H, Ro SW, Seo E, Ryu YM, Myung SJ, Jho EH.

Proc Natl Acad Sci U S A. , 2017 , 114:4691-4696.

4. Defective neuronal migration and inhibition of bipolar to multipolar transition of migrating neural cells by Mesoderm-Specific Transcript, Mest, in the developing mouse neocortex.

Ji L, Bishayee K, Sadra A, Choi S, Choi W, Moon S, Jho EH, Huh SO

Neuroscience , 2017 , 355:126-140

3. Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer.

Kim Y, Jho EH

BMB Reports , 2017 , 50(6):281-282

2. Interaction of Tankyrase and Peroxiredoxin II is Indispensable for the Survival of Colorectal Cancer Cells.

Kang DH, Lee DJ, Lee S, Lee SY, Jun Y, Kim Y, Kim Y, Lee JS, Lee DK, Lee S, Jho EH, Yu DY, Kang SW.

Nat Comm. , 2017 , 8(1):40

1. In vitro NLK Kinase Assay.

Moon S, Kim J, Jho E.

Bio-Protocol , 2017 , 7(21):1-10.

3. Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation.

Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J*, Jho EH*.

Cell Death and Diff. , 2016 , 23(10):1638-47

2. Mechanotransduction activates Canonical Wnt/b-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves.

Cha B, Geng X, Mahmud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon B, Chen H, Srinivasan RS.

Genes & Dev , 2016 , 30(12):1454-69

1. Merlin, a regulator of Hippo signaling, regulates Wnt/b-catenin signaling.

Kim S, Jho EH.

BMB Rep. , 2016 , 49:357-8.

3. Protein Arginine Methyltransferase 1 Methylates Smurf2.

Cha B, Park Y, Hwang BN, Kim SY, Jho EH.

Mol Cells. , 2015 , 38(8):723-8

2. Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells.

Kim H, Kim S, Song Y, Kim W, Ying QL, Jho EH.

Stem Cells Int. , 2015 , 2015:459301

1. Clinical analysis of spinal stereotactic radiosurgery in the treatment of neurogenic tumors.

Shin DW, Sohn MJ, Kim HS, Lee DJ, Jeon SR, Hwang YJ, Jho EH.

J Neurosurg Spine. , 2015 , 23(4):429-37

3. Acute gastroenteritis outbreaks associated with ground-waterborne norovirus in South Korea during 2008-2012.

Cho HG, Lee SG, Kim WH, Lee JS, Park PH, Cheon DS, Jheong WH, Jho EH, Lee JB, Paik SY

Epidemiol Infect. , 2014 , 142(12):2604-9

2. Molecular epidemiology of norovirus GII.4 variants in children under 5 years with sporadic acute gastroenteritis in South Korea during 2006-2013.

Cho HG, Lee SG, Kim JE, Yu KS, Lee DY, Park PH, Yoon MH, Jho EH, Kim J, Paik SY

J Clin Virol. , 2014 , 61:340-344

1. Cross-talk Between Wnt/β-catenin and Hippo signaling pathways: a brief review.

Kim M, Jho EH.

BMB Rep. , 2014 , 47:40-5

6. ADP-ribosylation factor regulates Wnt/b-catenin signaling via control of LRP6 phosphorylation.

Kim W, Kim SY, Kim T, Kim M, Bae DJ, Choi HI, Kim IS and Jho EH

Oncogene , 2013 , 32(28): 3390-6

5. High prevalence of amantadine-resistant influenza A virus isolated in Gyeonggi Province, South Korea, during 2005-2010.

Cho HG, Choi JH, Kim WH, Hong HK, Yoon MH, Jho EH, Kang C and Lim YH

Arch Virol. , 2013 , 158(1):241-5

4. Wnt/b-catenin signaling: From plasma membrane to nucleus.

Kim W, Kim M, and Jho EH.

Biochemical Journal , 2013 , 450(1):9-21

3. Axin expression enhances herpes simplex virus type 1 replication by inhibiting virus-mediated cell death in L929 cells.

Choi EJ, Kim S, Jho EH, Song KJ and Kee SH

J. Gen. Virol. , 2013 , 94(7):1636-46

2. Oseltamivir-resistant influenza viruses isolated in South Korea from 2005 to 2010

Cho HG, Choi JH, Lee HK, Mun SK, Lee JB, Jho EH, Kang C and Lim YH

Arch Virol. , 2013 , 158(11):2365-70

1. Deubiquitination of Dishevelled by Usp14 is required for Wnt Signaling.

Jung H, Kim BG, Han WH, Lee JH, Cho JY, Park WS, Maurice MM, Jan JK, Lee MJ*, Finley D* and Jho EH*.

Oncogenesis , 2013 , 2:e64

2. Protein arginine methyltransferases (PRMT) as therapeutic targets.

Cha B and Jho EH.

Expert Opinion on Therapeutic Targets , 2012 , 16(7):651-64

1. Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning.

Kim W, Kim H, Katanaev V, Lee S, Ishitani T, Cha B, Han JK* and Jho EH*

EMBO J. , 2012 , 31(16):3384-97.

6. Down-regulation of Wnt/b-catenin signaling causes degeneration of hippocampal neurons in vivo.

Kim H, Won S, Hwang DY, Lee JS, Kim M, Kim R, Kim W, Cha B, Kim T, Kim D, Costantini F, Jho EH.

Neuro. Aging. , 2011 , 32(12):2316.e1-2316.e15

5. Methylation by protein arginine methyltransferase1 increases stability of Axin, a negative regulator of Wnt signaling.

Cha B, Kim W, Kim YK, Hwang BN, Park SY, Yoon JW, Park WS, Cho JW, Bedford MT and Jho EH.

Oncogene , 2011 , 30(20):2379-89

4. PKC inhibitors RO 31-8220 and Gø 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation.

Kim SY, Kim S, Kim JM, Jho EH, Park S, Oh D and Yun-Choi HS

BMB Report , 2011 , 44(2):140-5

3. Mest/Peg1 inhibits Wnt signaling via regulation of LRP6 glycosylation.

Jung H, Lee SK and Jho EH.

Biochemical Journal , 2011 , 436(2):263-9

2. Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

Lyu J, Jho EH, Lu, W.

Cell Research , 2011 , 21(6):911-21

1. Wnt5a potentiates U46619-induced platelet aggregation via the PI3K/Akt pathway.

Kim SY, Kim S, Yun-Choi HS and Jho EH

Mol Cells. , 2011 , 32(4):333-6

2. Identification of ptpro as a novel target gene of Wnt signaling and its potential role as a receptor for Wnt.

Kim M, Kim H, Jho EH.

FEBS Letters , 2010 , 584(18):3923-28

1. The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad Ubiquitination Regulatory Factor 2 (Smurf2).

Kim SW, Jho EH

J. Biol. Chem. , 2010 , 285(47):36420-6

6. Multiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signaling.

Seo E, Kim H, Kim R, Yun S, Kim M, Han JK, Costantini F, Jho EH.

Cell Signal. , 2009 , 21:43-51

5. Induction of cancer cell-specific death via MMP2 promoter-dependent expression of Bax.

Seo E, Kim S, Jho EH.

BMB reports. , 2009 , 42(4):217-22

4. Axin localizes to mitotic spindles and centrosomes in mitotic cells.

Kim SM, Choi E, Song, K, Kim S, Seo E, Jho EH, Kee SH.

Exp Cell Res. , 2009 , 315(6):943-54

3. Xenopus Wntless and the Retromer complex cooperate to regulate XWnt4 secretion.

Kim H, Cheong SM, Ryu J, Jung HJ, Jho EH and Han JK.

Mol Cell Biol. , 2009 , 29(8):2118-28.

2. Identification of a Stroma-Mediated Wnt/β-catenin Signal Promoting Self-renewal of Hematopoietic Stem Cells in Stem Cell Niche.

Kim JA, Kang YJ, Park G, Kim M, Park YO, Kim H, Leem SH, Chu IS, Lee JS, Jho EH, Oh IH.

Stem Cells. , 2009 , 27(6):1318-29.

1. Negative feedback regulation of Wnt signaling by Gbg-mediated reduction of Dishevelled.

Jung H, Kim H, Lee SK, Kim R, Kopachik W, Han JK, Jho EH.

Exp. Mol. Med. , 2009 , 41(10):695-706

1. Olig2-induced neural stem cell differentiation involves downregulation of Wnt signaling and induction of Dickkopf-1 expression.

Ahn SM, Byun K, Kim D, Lee K, Yoo JS, Kim SU, Jho EH, Simpson RJ, Lee B.

PLoS ONE , 2008 , 3(12):e3917

5. Wnt/b -catenin signaling regulates expression of PRDC, an antagonist of the BMP-4 signaling pathway.

Im JM, Kim HJ, Kim SW, Jho EH

Biochem Biophys Res Commun. , 2007 , 354:296-301

4. Focal adhesion kinase is negatively regulated by phosphorylation at tyrosine 407.

Lim Y, Park H, Jeon J, Han, I, Kim J, Jho EH, Oh ES

J. Biol. Chem. , 2007 , 282(14):10398-404

3. Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via b-catenin.

Jeon S, Yoon J, Park Y, Jeong W, Kim S, Jho EH, Surh Y, Choi K.

J. Biol. Chem. , 2007 , 282:14482-92

2. Axin-independent phosphorylation of APC controls b-catenin signaling via cytoplasmic retention of b-catenin.

Seo E, Jho EH.

Biochem Biophys Res Commun. , 2007 , 357:81-6

1. Induced expression of the transcription of tropomodulin 1 by Wnt5a and characterization of the tropomodulin 1 promoter.

Yun S, Rim Y, Jho EH.

Biochem Biophys Res Commun. , 2007 , 363:727-32

2. Multinuclear giant cell formation is enhanced by down-regulation of Wnt signaling in gastric cancer cell line, AGS.

Kim SM, Kim R, Ryu JH, Jho EH, Song KJ, Jang SI, Kee SH.

Exp Cell Res , 2005 , 308:18-28.

1. The role of GDNF in patterning the excretory system.

Shakya R, Jho EH, Kotka P, Wu Z, Kholodilov N, Burke R, D'Agati V, Costantini F.

Dev Biol. , 2005 , 283:70-84

6. Accumulation and aberrant modifications of alpha-crystallins in anterior polar cataracts.

Hwang KH, Lee EH, Jho EH, Kim JH, Lee do H, Chung SK, Kim EK, Joo CK.

Yonsei Med J. , 2004 , 45:73-80

5. Cyclin-dependent kinase 2 regulates the interaction of Axin with b-catenin.

SI Kim, CS Park ,MS Lee, MS Kwon, EH Jho, WK Song,

Biochem Biophys Res Commun. , 2004 , 317:478-483.

4. Modulation of beta -catenin phosphorylation/degradation by cyclin-dependent kinase 2.

Park CS, Kim SI, Lee MS, Youn CY, Kim DJ, Jho EH, Song WK,

J. Biol. Chem. , 2004 , 279 :19592-9

3. Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms.

Hwang SG, Ryu JH, Kim IC, Jho EH, Jung HC, Kim K, Kim SJ, Chun JS.

J. Biol .Chem. , 2004 , 279 :26597-604

2. Hydrogen peroxide negatively modulates Wnt signaling through down regulation of beta-catenin.

Shin SY, Kim CG, Jho EH, Rho MS, Kim YS, Kim YH, Lee YH.

Cancer Lett. , 2004 , 212:225-31.

1. APC is down-regulated by the ubiquitin-proteasome pathway in a process facilitated by Axin.

Choi JK, Park SY, Costantini F, Jho EH*, Joo CK*.

J. Biol. Chem. , 2004 , 279:49188-98.

1. Ectopic expression of Axin blocks neuronal differentiation of embryonic carcinoma P19 cells.

Lyu J, Costantini F, Jho EH*, Joo CK*

J. Biol. Chem. , 2003 , 278:13487-95

7. C-jun amino-terminal kinase is regulated by Ga12/Ga13 and obligate for differentiation of P19 embryonal carcinoma cells by the retinoic acid.

Jho, E., Davis, R. J. and Malbon, C.

J. Biol. Chem. , 2002 , 272, 24468-74

6. Ga12 and Ga13 mediate differentiation of P19 mouse embryonal carcinoma cells in response to retinoic acid.

Jho, E. and Malbon, C.

J. Biol. Chem. , 2002 , 272, 24461-67

5. Domains of Axin Involved in Protein-Protein Interactions, Wnt Pathway Inhibition, and Intracellular Localization.

Fagotto F*, Jho E*, Zeng L, Kurth T, Joos T, Kaufmann C and Costantini F.

J. Cell Biol. , 2002 , 145,741-756.

4. A GSK3b phosphorylation site in Axin modulates interaction with b-catenin and Tcf-mediated gene expression.

Jho, E., Lomvardas, S. and Costantini, F.

Biochem Biophys Res Commun. , 2002 , 266, 28-35.

3. Purification of GSK-3 by Affinity Chromatography on Immobilized Axin.

Primot A, Baratte B, Gompel M, Borgne A, Liabeuf S, Romette JL, Jho E, Costantini F, Meijer L.

Protein Expr Purif , 2002 , 20, 394-404.

2. Domains of Axin and Disheveled required for interaction and functions in Wnt signaling.

Julius, M., Schelbert, B., Hsu, W., fitzpatrick, E., Jho, E., Fagotto, F., Costantini, F. and Kitajewski, J.

Biochem Biophys Res Commun , 2002 , 276,1162-9

1. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.

Jho, E., Zhang, T., Domon, C., Joo, C.-k., Freund, N. and Costantini, F.

Mol Cell Biol. , 2002 , 22, 1172-83.