Seminars

Our laboratory is dedicated to advancing organoid-based precision medicine by visualizing complex biological mechanisms and constructing integrated biological and mathematical models of disease. Through these efforts, we aim to bridge fundamental discoveries with clinically relevant applications.

In particular, we are actively developing novel and diverse neural organoid platforms that incorporate iPSC-derived microglia. These platforms provide a powerful means to investigate microglia–neuron (or other glial cells) interactions and can be applied to a wide range of neurodegenerative diseases, including Alzheimer’s disease and related disorders. By using such models, we hope to reveal disease-specific mechanisms, identify therapeutic targets, and ultimately accelerate translational research.

In this presentation, I will introduce the diverse neural organoid platforms established in our lab and highlight our most recent findings from iPSC-derived microglia research, which is currently one of our most active areas of investigation. Through this, we aim not only to share our progress but also to foster enthusiastic collaboration with other researchers working across related fields.